Players tried different tactics - trying to connect their Destinations first, or accruing points early by building the longest routes - but the scores were pretty close. James just managed to add to his track in the last couple of turns to get the same length route as Adrian, preventing the 10 point bonus taking Adrian past him. So the final scores were James (Red) 112, Adrian (Blue) 105, Kieron (Yellow) 94, Andy (Green) 82 and Russell (Black) 68 - unusually not winning this visit.
There was some discussion about whether the "longest continuous path of routes" meant the most trains of one colour which were connected, or the longest path traced by those trains without branching. Posts on the Board Game Geek forum here and here say the latter, so that's what we'll play. It didn't affect the final player order in this game, but would have brought Andy's score to just a scrape behind Kieron.
Since it wasn't a school night, we brought Medici back out for another outing. Adrian was alone in remembering exactly how he'd creamed us last time we played this, and so he thrashed us again. Adrian 129, Russell 100, James 98, Kieron 96 and Andy 65.
A fun games night punctuated by hacking coughs from most of the participants.

Andy had a small battle with Kieron and held on to the far eastern island, and also briefly visited the Kieron/James naval warfare to take out James' well-placed fort before it could do to much damage to Kieron. David had a quiet but effective early game, eventually succumbing and attacking Andy in order to see a bit of action. The end result looked like this...